Further, overexpression of miR-1244 suppressed cell viability and increased apoptosis in the standard NSCLC cell lines by promoting caspase-3 activity, p53 and Bax protein expression, and suppressing myocyte enhancer factor 2D (MEF2D) and cyclin D1 protein expression. The gene discussed is MEF2D; the disease is non-small cell lung carcinoma.