To further explore genomic effects of AICDA overexpression, we performed whole exome sequencing in VavP-Bcl2+Aicda (n = 4) and VavP-Bcl2 lymphomas (n = 4) and found no significant difference in nonsynonymous or indel mutation burdens (Supplementary Fig. 4c, d). Here, BCL2 is linked to lymphoma.