SQSTM1 and amyotrophic lateral sclerosis: The ubiquitin‐proteasomal system, important for maintaining protein quality control, is also compromised in experimental models of familial ALS (Cheroni et al, 2009; Dantuma & Bott, 2014; Scotter et al, 2014), and increased levels of autophagy/mitophagy markers, LC3BII and p62, have been reported in ALS models (Soo et al, 2015; Goode et al, 2016; Oakes et al, 2017).