TNF and retinitis pigmentosa: Similarly, calpain‐mediated caspase‐12 activation is also involved in TNF‐α‐induced apoptosis in cardiomyocytes (Bajaj & Sharma, 2006), neuron apoptosis in retinitis pigmentosa (Sanges et al, 2006), and hydroxyeicosatetraenoic acid‐induced fibroblast apoptosis (Nieves & Moreno, 2007).