Four genes in a complex region on chromosome 16 associated with COPD in an exome array study [41] were identified in the Sherlock analysis and in the eQTL-GWAS intersection: TUFM (Tu translation elongation factor, mitochondrial), EIF3CL (eukaryotic translation initiation factor 3 subunit C like), SULT1A1 (sulfotransferase family 1A member 1), and SULT1A2 (sulfotransferase family 1A member 2). The gene discussed is TUFM; the disease is chronic obstructive pulmonary disease.