FOXP3 and neoplasm: It is well known that tumor escape from immunosurveillance is favored by infiltration of the tumor by different populations of suppressor cells such as CD4+ CD25+ FoxP3+ regulatory (Tregs) [15], suppressor macrophages [16], Myeloid Derived Suppressor Cells (MDSCs) [17], and immature DCs, that inhibit tumor-specific T cells favoring escape from immune surveillance.