Group two consisted of 13 genes co-mentioned frequently with allergy-related terms since, but not before, 2007: ORMDL3, GSDMB, ZPBP2, IKZF3, GSDMA, IL6R, CHIT1, FCER1G, SLC22A5, WDR36, IL18RAP, HLA-DQA2 and NDFIP1. The first five are located in the same asthma risk locus, and were first suspected to contribute to asthma pathophysiology because of GWAS findings. This evidence concerns the gene IL6R and allergic disease.