Many neoplasms, including carcinomas of breast, prostate, lung, colon, bladder, esophagus, as well as lymphomas, neuroblastomas and osteosarcomas, were previously shown to overexpress survivin (Tanaka et al. 2000; Xing et al. 2001; Kato et al. 2001). This evidence concerns the gene BIRC5 and osteosarcoma.