Subarachnoid haemorrhage and APOE ɛ4 possession or finger-like projections, separated high from low or medium probability groups (appendix), and had a specificity of 96% (95% CI 78–100; appendix) meaning that the presence of these predictors with lobar intracerebral haemorrhage ruled in moderate or severe CAA. The gene discussed is APOE; the disease is intracerebral hemorrhage.