Whilst the frequency of model predictors (APOE ɛ4 possession, subarachnoid haemorrhage and finger-like projections) and the distribution of risk categories did not vary between those participants who underwent autopsy and those participants who did not undergo autopsy (appendix), the applicability of our criteria to other intracerebral haemorrhage groups—such as younger patients with smaller intracerebral haemorrhage—is unclear. This evidence concerns the gene APOE and intracerebral hemorrhage.