CRP and coronary artery disorder: Moreover, some data suggest that CRP is directly involved in the pathogenesis of coronary heart diseases [12]: it participates in atherogenesis via modulating the expression of genes encoding vascular cell adhesion molecule 1 (VCAM-1), intracellular adhesion molecule 1(ICAM-1), selectin, and monocyte chemotactic protein (MCP-1) in endothelial cells [13–15].