TPO and autoimmune thrombocytopenic purpura: Eltrombopag (ELT), an oral non-peptide TPO-RA which could facilitate the proliferation and differentiation of megakaryocytes and increase platelet production10, has been approved by the United States Food and Drug Administration (FDA) for pediatric patients (≥1 year old) with chronic ITP who have “not achieved an appropriate response using other ITP medicines or splenectomy”11.