EPHB4 and Miyoshi myopathy: Molecular pathways such as RANK/RANKL/OPG, Notch, Wnt, RUNX2, EphrinB2/EphB4, and TNF pathway, as well as signaling molecules including DKK1, sclerostin, periostin, osteopontin, GFI1, BMPs, TGFβ, activin A, annexin II, adiponectin, BTK, SDF1a, chemokines, and interleukins, are at the spotlight of current MM research (Table 1).