It is currently unclear as to how activating ABCC9 mutations lead to hypertrichosis, acromegaloid facial features, osteochondrodysplasia, and cardiovascular anomalies, while these features remarkably overlap with the side-effects of minoxidil, which binds to SUR2 resulting in ATP-sensitive potassium channel opening and activation [3]. The gene discussed is ABCC9; the disease is hypertrichosis.