RUNX3 and asthma: RUNX1 and RUNX3 influence the development and function of TH1, TH2, TREG, and TH17 cells, which regulate autoimmunity, asthma, allergic responses, and tumor immunity (Djuretic et al., 2007, 2009; Naoe et al., 2007; Ono et al., 2007; Zhang et al., 2008; Bruno et al., 2009; Wong et al., 2011).