One group sequenced AML samples from 9 Japanese FPD/AML patients and reported somatic mutations in CDC25C in 4 patients, concluding that somatic mutations in CDC25C (which are rarely observed in sporadic AML) were the most common genetic event in AML arising from FPD/AML (Yoshimi et al., 2014; Sakurai et al., 2016). The gene discussed is CDC25C; the disease is acute myeloid leukemia.