In 2016, Gossai et al. functionalized 15 nm AuNPs with dsDNA oligonucleotides with a sequence corresponding to BIRC5, a gene is overexpressed in CML cell lines, which was further loaded with dasatinib, a potent TKI frequently used against CML. The gene discussed is BIRC5; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.