TNFRSF4 and HIV-1 infection: RNA-seq analysis of ILC in human subjects with acute HIV-1 infection showed that there was a downregulation of genes associated with viability (89), and gene array analysis (87) showed that mucosal IL-17+ cells highly expressed TNF-receptor superfamily 4 (TNFRSF4, OX40), a co-stimulatory molecule involved in maintenance of mucosal lymphocytes, in comparison to IL-17− cells (104–106).