Some of the most well-known chemokines associated with tumor progression and angiogenesis are fibroblast growth factor, stromal-derived growth factor-1α (SDF-1α/CXCL12), vascular endothelial growth factor-A (VEGF-A), granulocyte–macrophage colony-stimulating factor (GM-SCF), granulocyte colony-stimulating factor (G-CSF), platelet-derived growth factor (PDGF), epidermal growth factor (EGF), angiopoietin-1, monocyte chemoattractant protein-1 (MCP-1/CCL2), hematopoietic growth factor, transforming growth factor beta-1 (TGF-β1) IL-8, IL-6, and urokinase-type plasminogen activator (6, 73, 74). This evidence concerns the gene EGF and neoplasm.