These include patients with unstable angina (1.04 ± 0.08 ng/mL), acute myocardial infarction (1.07 ± 0.11 ng/mL), and asymptomatic coronary artery disease (2.1 ± 0.8 ng/mL), which have all been shown to have lower total ghrelin concentrations compared to controls (6.2 ± 4.1 ng/mL) (88). This evidence concerns the gene GHRL and coronary artery disorder.