The mRNA expression levels for the third NSC marker, Musashi-1 (MSI1), were found to be significantly reduced in ALS patients compared to controls within SC (p = 0.006; Figure 10C) as well as in MC (p = 0.015; Figure 10C), but unchanged for OL (p = 0.983; Figure 10C). Here, MSI1 is linked to amyotrophic lateral sclerosis.