Our finding that NRG1 rs10503929 TT genotype carriers had significantly less disorganized symptoms than the dominant (CC + CT) genotype carriers at baseline (RDoC cognitive control) is consistent with previous finding of a significant association of NRG1 rs10503929 with cognitive domains (abstraction and mental flexibility, attention, and verbal memory) in schizophrenia patients, in which the C-allele (protective against schizophrenia) was associated with decreased cognitive performance (55). Here, NRG1 is linked to schizophrenia.