AQP4 and ischemic stroke: Either way, it is interesting to note that it had been demonstrated in a previous study that Edaravone, a free radical scavenger commonly prescribed for the treatment of ischemic stroke, inhibits AQP4 expression in the infarct area (Kikuchi et al., 2009), as does Resveratrol, a phytological polyphenol that may have antioxidant properties (Li et al., 2015).