Moreover, hnRNPA1 also co-localizes with RNA foci in C9-FTD/ALS patient-derived iPSNs (Sareen et al., 2013), whereas SRSF1 and SRSF2 co-localizes with cerebellar RNA foci, but is relatively occasional (Lee et al., 2013). This evidence concerns the gene SRSF1 and amyotrophic lateral sclerosis.