DNMT3A and B-cell chronic lymphocytic leukemia: To do this, we assessed DMRs recently reported by Haney et al., contrasting splenic B-1a cells from a Dnmt3a+/+ control mouse and a EμSRα-tTA;Teto-Cre;Dnmt3afl/fl;Rosa26LOXPEGFP/EGFP (Dnmt3aΔ/Δ) mouse with CLL (Haney et al. 2016a).