Other examples include ventricular septal defect and developmental pattern specification process, which are both targeted by SUZ12 and CTBP2, PECAM1 Interactions and disease agammaglobulinemia targeted by EBF1, intestinal disease and Human immunodeficiency virus infectious disease both targeted by NFKB1, prostate cancer and intestinal cancer both targeted by TP53, and Metalloendopeptidase Activity and cognitive disorder both targeted by ETV4, among many others. The gene discussed is TP53; the disease is Cognitive impairment.