A statistically significant difference in haplotype distribution between the groups of MS patients and healthy controls was found at both gene loci: at ARNTL gene locus for haplotype CGG (P = 4.00·10−3) and TGA (P = 0.03) and at CLOCK gene locus for haplotype TCAG (P = 1.00·10−3) (Tables 3 and 4). Here, CLOCK is linked to myeloid sarcoma.