Genotype and allelic distribution of the ARNTL and CLOCK polymorphisms in MS patients and healthy controls are shown in Table 1.We found a statistically significant difference in the genotype distribution of rs3789327 in ARNTL gene (P = 7.5·10−5) and rs6811520 in CLOCK gene (P = 0.02). Here, CLOCK is linked to myeloid sarcoma.