Colony-stimulating factor 1 receptor (CSF1R) tyrosine kinase inhibition reduces murine PCa TAMs 15-fold, lowers expression of the Vegfa, Mmp9, and Arg1 M2 mRNAs in the remaining TAMs, and delays tumor progression, with similar findings in immune-deficient mice inoculated with a human PCa line [8]. This evidence concerns the gene ARG1 and posterior cortical atrophy.