In univariate regression models being registered before/in 2007 (OR = 3.63; [95%CI:2.27–5.80]), not being infected through homosexual mode (3.92;[2.49–6.15]), female gender (3.79;[2.55–5.64]), positive HCV RNA (1.78; [1.15–2.78]) were increasing and higher nadir lymphocyte CD4+ count (0.85;[0.80–0.92]), model being on ARV (0.90; [0.322–2.529]) was decreasing the odds of first urinary tract infection. The gene discussed is CD4; the disease is urinary tract infection.