Curtis et al. [37] shows basal-like cancer enriched subgroup, harbours chromosome 5q deletions, and several signaling molecules, transcription factors and cell division genes were associated in trans with this deletion event in the basal cancers, including alterations in BUB1, CDCA4, CHEK1, FOXM1, HDAC2, KIFC1, MTHFD1L, RAD51AP1, TTK. This evidence concerns the gene CHEK1 and cancer.