The common pathways observed in chickens with low loads of S. Enteritidis included: chemokine signaling pathway, Fc ε RI signaling pathway, focal adhesion, insulin signaling pathway, Jak–Stat signaling pathway, mitogen-activated protein kinase (MAPK) signaling pathway, neurotrophin signaling pathway, pathways in cancer, T cell receptor signaling pathway, and Tuberculosis. The gene discussed is INS; the disease is cancer.