Specifically, 3 genes have been associated with atherothrombotic stroke subtype (HDAC9, CDKN (locus 9p21) and TSPAN2), 2 genes with cardioembolic stroke subtype (PITX2 and ZFHX3), and 2 genes with young strokes (ABO and MMP12). The gene discussed is PITX2; the disease is stroke disorder.