CD4 and systemic lupus erythematosus: Given that pro-inflammatory cytokines are crucial in lupus pathogenesis (78, 79), we also measured the cytokine production level in vitro that WT or B7-H4-KO BMDCs incubated with ALD-DNA and then co-cultured with wild-type normal CD4+ cells supernatants used a cytokine test kit named CBA (BD).