ARC and schizophrenia: Arc response to memory and learning stimuli may account for a direct involvement of this IEG into dopaminergic-dependent mechanisms of memory consolidation, as well as for its implication in dopamine-glutamate subcellular interactions that control synaptic plasticity processes thought to be dysfunctional in the pathophysiology of schizophrenia (Eastwood, 2004; Grant, 2012; Yin et al., 2012).