These include the leucine-rich repeat kinase 2 (LRRK2) pathway in Parkinson’s disease (FDR-adjusted P = 9.4e-5, Fig. 3) and PD-1/PD-L1 (Programmed Death 1/PD-Ligand 1) signaling pathway (FDR-adjusted P = 6.5e-5, Fig. 4). The gene discussed is CD274; the disease is Parkinson disease.