TIPE1 and hepatocellular carcinoma: Examples of these include Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death [28], Cisplatin-induced apoptosis in NIH3T3 cells [29], UV-induced apoptosis in COS-1 cells [30], TIPE1- induced apoptosis in hepatocellular carcinoma cells [31], and TNF-α-induced apoptosis in endothelial cells [32].