THBD and tuberculosis: IFN-DCs from active TB patients (TB-DCs), compared to LTBI (LTBI-DCs) and HD (HD-DCs) counterparts, exhibited significant lower levels of both BDCA-3 and CD123 whereas the down-modulation of the BDCA-1 myeloid marker was comparable in both Mtb infected groups compared to HD (Fig 1C).