YBX1 and cancer: In this study, the serial cell counting has shown a significant (p < 0.05) reduction in cancer cell proliferation among P1 and P2 YB-1 silenced cell strains in comparison with Pc cell strain as shown in Figure 5A. The MTT results were compatible with the cell counting findings, showing a highly significant reduction in the optical density among P1 and P2 YB-1 silenced cell strains in comparison with Pc cell strain as shown in Figure 5B. Moreover, the flow-cytometry results have shown YB-1 as a cell cycle specific regulator of cell proliferation as shown in Figure 5C,D.