No differences were observed in the data of GPA patients between the winter/spring season (n=32) and the summer/autumn (n=27) relative to the BVAS/WG (1.37±2.49 vs. 1.70±1.81, p=0.28), VDI (5.50±2.25 vs. 5.29±2.30, p=0.36), WBC (7,435±2,943 vs. 6,711±2,209/mm3, p=0.14), ESR (13.41±16.94 vs. 13.41±12.94 mm/h, p=0.49) and CRP level (6.00±10.72 vs. 10.49±23.71 mg/L, p=0.17). This evidence concerns the gene ESR1 and granulomatosis with polyangiitis.