In the same line, [41] have demonstrated that treating T1D patients with autologous hematopoietic stem cell transplantation (AHSCT) reduced Th1 and Th17 cell expansion and function as well as decreasing IFN-γ, IL-2, IL-12p40, and IL-17A levels in the supernatants of peripheral blood mononuclear cell culture. The gene discussed is IFNG; the disease is type 1 diabetes mellitus.