ARID1A and gastric cancer: Furthermore, to ascertain whether miR-223-3p could directly target the 3′-untranslated region (UTR) of ARID1A in gastric cancer cells, we constructed a wild-type luciferase reporter vector (WT) containing the targeting sequences of ARID1A 3′-UTR and a mutant luciferase reporter vector (Mut) in which the targeting sequences were mutated (Fig. 4e).