We found that EZH2 and H3K27me3 were moderately enriched in the indicated regionin HCC cells and thatEZH2 and H3K27me3 enrichment was significantly decreased in shEZH2-transfected cells but was significantly enhanced in pCMV EZH2-transfected cells (Fig. 4h). The gene discussed is EZH2; the disease is hepatocellular carcinoma.