Further, SCA subtypes caused by expansions in non-coding regions of genes responsible for SCA8, SCA10, SCA12 and SCA36 as well as other ataxias known to be associated with repeat expansions such as fragile X-associated tremor ataxia syndrome (FXTAS) should be taken into account before applying NGS-based diagnostics. The gene discussed is PPP2R2B; the disease is cerebellar ataxia.