Second, not surprisingly, with 18.8% and 7.4% of all translocations, t(9;22)(q34;q11) and t(8;21)(q22;q22)—corresponding to the Philadelphia chromosome/BCR-ABL1 and RUNX1-RUNX1T1/AML1-ETO fusion genes [12,15]—were the most frequent translocations in blood cancers (Figure 6d, Supplementary Figure S1, Table S2). This evidence concerns the gene RUNX1 and hematopoietic and lymphoid system neoplasm.