Examples include RUNX1-RUNX1T1 (formerly AML1-ETO) fusion genes, which are the result of common t(8;21)(q22;q22) translocations in acute myeloid leukemia (AML) patients [16] and BCR-ABL1 fusion genes caused by t(9;22)(q34;q11) translocations in chronic myeloid leukemia (CML) patients [17]. The gene discussed is BCR; the disease is acute myeloid leukemia.