When considered together with the previously shown prosurvival function of FOXG1 and TLE1 in healthy neurons (Dastidar et al., 2011, 2012), these observations suggest that FOXG1:TLE1 may promote glioma cell survival, at least in part, through inhibition of the pro‐apoptotic function of CHAC1 (Fig. 5G). This evidence concerns the gene FOXG1 and central nervous system cancer.