When considered together with the previously shown prosurvival function of FOXG1 and TLE1 in healthy neurons (Dastidar et al., 2011, 2012), these observations suggest that FOXG1:TLE1 may promote glioma cell survival, at least in part, through inhibition of the pro‐apoptotic function of CHAC1 (Fig. 5G). The gene discussed is TLE1; the disease is glioma.