More importantly, mRNA expression of CHAC1 and FOXG1 in selected samples from the MediSapiens database (Kilpinen et al., 2008) and The Cancer Genome Atlas showed an inverse correlation of FOXG1 (high) and CHAC1 (low) levels in GBM; in contrast, the opposite situation was observed in mesenchymal stem cells (Fig. 5C; Fig. S2). This evidence concerns the gene FOXG1 and glioblastoma.