Integration of the SOX10 phosphorylation sites discovered in our mass spectroscopy analysis with those identified in previous studies in breast cancer, neuroblastoma and melanoma cells indicates that SOX10 phosphorylation occurs in two distinct clusters close to SOXE-conserved domains [50–52,66,67] (Fig 2), highlighting two regions available for protein-protein interactions leading to post-translational modifications. Here, SOX10 is linked to neuroblastoma.