IL-1β, IL-6, and TNF-α are considered pro-inflammatory cytokines, and, likewise, NF-κB, can be both associated to tumor progression (promoting tumor growth, invasiveness, and metastasis) or rejection (through antitumor immunity and induction of cell death), depending on the context and the tumor model [160,161,162,163,164,165,166,167,168]. This evidence concerns the gene IL1B and neoplasm.