SCHLAP1 and neoplasm: As shown by Prensner, even though “other lncRNAs, such as HOTAIR and HOTTIP, are known to assist epigenetic complexes such as PRC2 and MLL by facilitating their genomic binding and enhancing their functions, SChLAP1 is the first lncRNA that impairs a major epigenetic complex with well-documented tumor suppressor function” (41, 44).