Finally, CREBBP (DC = 190, BC = 512,840.8) and CDK2 (DC = 170, BC = 409,517.7) were recorded as the most potential hub genes in Cancer versus CIN group, whereas HDAC1 was a relatively low connected gene in this group (DC = 18, BC = 30,041.4). This evidence concerns the gene HDAC1 and breast cancer.