LEPR and esophageal squamous cell carcinoma: In the stratified analyses, LEPR rs6588147 G>A polymorphism increased the risk of ESCC (<63 years subgroup: AA vs. GG: adjusted OR=2.58, 95%CI=1.00–6.62, P=0.049 and AA vs. GA/GG: adjusted OR=2.71, 95%CI=1.06–6.91, P=0.038; male subgroup: AA vs. GG: adjusted OR=2.19, 95%CI=1.02–4.67, P=0.044 and AA vs. GA/GG: adjusted OR=2.26, 95%CI=1.06–4.80, P=0.035).