MMP1 and neoplasm: Using the dpp>lgl-RNAi tumor enhancer screen, we tested 28 (available fly stocks, Supplementary Table 2) miRNAs upregulated in the lgl-RNAi-induced tumors, and found that 10 of them induced tumorigenic overgrowth and upregulation of MMP1, indicating a metastatic potential for the tumors (Figure 3C–3F’’).