MKI67 and neoplasm: The Ki-67 labelling index, which is usually related to the clinical course of tumor, is significantly lower in Curcumin/MPEG-PLA micelles group (24.3 % ± 8.1 %) than other groups (87.7 % ± 6.8 % in NS group, P < 0.05; 86.3% ± 7.1 % in blank micelle group, P < 0.05; 51 % ± 8 % in free Curcumin group, P < 0.05).